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He, Chuan
One or more keywords matched the following items that are connected to He, Chuan
Item TypeName
Concept Leukemia
Concept Models, Chemical
Concept Models, Molecular
Concept Mice, Transgenic
Concept Models, Genetic
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Humans
Concept Linear Models
Concept Leukemia, Myeloid
Concept Leukemia, Myeloid, Acute
Concept Mice, Knockout
Concept Gene Expression Regulation, Developmental
Concept Embryonic Development
Concept Growth and Development
Concept Mice
Concept Models, Statistical
Concept Leukemia, Promyelocytic, Acute
Concept Genome, Human
Concept Myeloid-Lymphoid Leukemia Protein
Concept Disease Models, Animal
Concept Models, Biological
Concept Mice, SCID
Concept Mice, Inbred NOD
Academic Article Intramolecular amide bonds stabilize pili on the surface of bacilli.
Academic Article Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs.
Academic Article The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.
Academic Article Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Academic Article A selective fluorescent probe for carbon monoxide imaging in living cells.
Academic Article Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.
Academic Article The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis.
Academic Article Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.
Academic Article The structure of the human AGT protein bound to DNA and its implications for damage detection.
Academic Article A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
Academic Article Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Academic Article Binding of ReO4(-) with an engineered MoO4(2-)-binding protein: towards a new approach in radiopharmaceutical applications.
Academic Article N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
Academic Article Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Academic Article Selective fluorescent probes for live-cell monitoring of sulphide.
Academic Article FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.
Academic Article HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.
Academic Article TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Academic Article Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Academic Article Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging.
Academic Article Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation.
Academic Article N6-methyladenosine-dependent regulation of messenger RNA stability.
Academic Article Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
Academic Article ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Academic Article Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
Academic Article Gene expression regulation mediated through reversible m6A RNA methylation.
Academic Article The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.
Academic Article Preparation of DNA containing 5-hydroxymethyl-2'-deoxycytidine modification through phosphoramidites with TBDMS as 5-hydroxymethyl protecting group.
Academic Article Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.
Academic Article Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Academic Article An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe.
Academic Article Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Academic Article Grand challenge commentary: RNA epigenetics?
Academic Article Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.
Academic Article Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.
Academic Article A diazirine-based nucleoside analogue for efficient DNA interstrand photocross-linking.
Academic Article Dynamic RNA modifications in posttranscriptional regulation.
Academic Article Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response.
Academic Article Pseudouridine in a new era of RNA modifications.
Academic Article Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Academic Article Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling.
Academic Article Aureusimines in Staphylococcus aureus are not involved in virulence.
Academic Article Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA.
Academic Article N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions.
Academic Article High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing.
Academic Article Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.
Academic Article A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells.
Academic Article Silver-catalyzed intermolecular amination of C--H groups.
Academic Article TET family proteins: oxidation activity, interacting molecules, and functions in diseases.
Academic Article Chemical methods to study protein-nucleic acid interactions.
Academic Article Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
Academic Article Introduction: epigenetics.
Academic Article How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases.
Academic Article Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states.
Academic Article Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.
Academic Article A non-heme iron-mediated chemical demethylation in DNA and RNA.
Academic Article Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions.
Academic Article Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins.
Academic Article Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
Academic Article Cancer: Damage prevention targeted.
Academic Article Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.
Academic Article Nucleic acid modifications with epigenetic significance.
Academic Article Mapping recently identified nucleotide variants in the genome and transcriptome.
Academic Article Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage ß-glucosyltransferase.
Academic Article Direct reversal of DNA alkylation damage.
Academic Article Reversible RNA adenosine methylation in biological regulation.
Academic Article Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
Academic Article Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
Academic Article Nucleic acid oxidation in DNA damage repair and epigenetics.
Academic Article Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
Academic Article In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS.
Academic Article Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.
Academic Article Reading RNA methylation codes through methyl-specific binding proteins.
Academic Article Synthesis of a FTO inhibitor with anticonvulsant activity.
Academic Article Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.
Academic Article Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
Academic Article Modeling non-heme iron proteins.
Academic Article Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Academic Article Gold(I)-catalyzed formation of 3-pyrazolines through cycloaddition of diaziridine to alkynes.
Academic Article A protein engineered to bind uranyl selectively and with femtomolar affinity.
Academic Article Engineering bacterial two-component system PmrA/PmrB to sense lanthanide ions.
Academic Article Live Cell MicroRNA Imaging Using Cascade Hybridization Reaction.
Academic Article N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.
Academic Article RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation.
Academic Article Decoding the transcriptome and DNA methylome of human primordial germ cells.
Academic Article High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy.
Academic Article Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity.
Academic Article Efficient and quantitative high-throughput tRNA sequencing.
Academic Article Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
Academic Article Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing.
Academic Article Detecting hepatocellular carcinoma in blood.
Academic Article RNA epigenetics--chemical messages for posttranscriptional gene regulation.
Academic Article The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA.
Academic Article Nucleic Acid Modifications in Regulation of Gene Expression.
Academic Article Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia.
Academic Article A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
Academic Article Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig.
Academic Article ALKBH1-Mediated tRNA Demethylation Regulates Translation.
Academic Article Post-transcriptional gene regulation by mRNA modifications.
Academic Article The emerging biology of RNA post-transcriptional modifications.
Academic Article FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.
Academic Article Evolution of transcript modification by N6-methyladenosine in primates.
Academic Article Developing drugs targeting transition metal homeostasis.
Academic Article YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
Academic Article m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition.
Academic Article Nm-seq maps 2'-O-methylation sites in human mRNA with base precision.
Academic Article DNA N6-methyladenine in metazoans: functional epigenetic mark or bystander?
Academic Article Dynamic RNA Modifications in Gene Expression Regulation.
Academic Article Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
Academic Article Chemical Modifications in the Life of an mRNA Transcript.
Academic Article RNA modifications modulate gene expression during development.
Academic Article Epigenetics: Making your mark on DNA.
Academic Article m6A facilitates hippocampus-dependent learning and memory through YTHDF1.
Academic Article FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function.
Academic Article Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition.
Academic Article Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis.
Academic Article RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.
Academic Article Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.
Academic Article m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
Academic Article Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs.
Academic Article YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs.
Academic Article Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis.
Academic Article Epitranscriptomic influences on development and disease.
Academic Article "Gamete On" for m6A: YTHDF2 Exerts Essential Functions in Female Fertility.
Academic Article Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation.
Academic Article Kinetic gating mechanism of DNA damage recognition by Rad4/XPC.
Academic Article High-Resolution Mapping of N 6-Methyladenosine Using m6A Crosslinking Immunoprecipitation Sequencing (m6A-CLIP-Seq).
Academic Article Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome.
Grant Mechanisms of Pancreatic Cancer Inhibition by SPARC
Grant Mechanism of SPARC peptide FSEC inhibition of angiogenesis in neuroblastoma
Academic Article Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis.
Academic Article Regulation of Gene Expression by N6-methyladenosine in Cancer.
Academic Article Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
Academic Article Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA.
Academic Article METTL14 is essential for ß-cell survival and insulin secretion.
Academic Article m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
Academic Article FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.
Academic Article Detailed modeling of positive selection improves detection of cancer driver genes.
Academic Article Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG.
Academic Article Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA.
Academic Article Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma.
Academic Article The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs.
Academic Article 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Academic Article RADAR: differential analysis of MeRIP-seq data with a random effect model.
Academic Article m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination.
Academic Article N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription.
Academic Article Keth-seq for transcriptome-wide RNA structure mapping.
Academic Article DNA 5-Methylcytosine-Specific Amplification and Sequencing.
Academic Article N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
Academic Article Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ.
Academic Article YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators.
Academic Article REPIC: a database for exploring the N6-methyladenosine methylome.
Academic Article Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation.
Academic Article Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability.
Academic Article A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells.
Academic Article Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution.
Academic Article Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation.
Academic Article N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
Academic Article A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.
Academic Article m6 A RNA methylation: from mechanisms to therapeutic potential.
Academic Article Chromatin and transcriptional regulation by reversible RNA methylation.
Academic Article N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
Academic Article Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis.
Academic Article Transcriptome-Wide Detection of Internal N7-Methylguanosine.
Academic Article ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.
Academic Article Functional analysis of a SOX10 gene mutation associated with Waardenburg syndrome II.
Academic Article Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations.
Academic Article Identification and functional analysis of a novel mutation in the SOX10 gene associated with Waardenburg syndrome type IV.
Academic Article METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
Academic Article HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.
Academic Article The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation.
Academic Article Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review.
Academic Article m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome.
Academic Article FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development.
Academic Article Development of Mild Chemical Catalysis Conditions for m1A-to-m6A Rearrangement on RNA.
Academic Article Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution.
Academic Article spKAS-seq reveals R-loop dynamics using low-input materials by detecting single-stranded DNA with strand specificity.
Academic Article Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma.
Academic Article N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis.
Academic Article Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination.
Academic Article Exon architecture controls mRNA m6A suppression and gene expression.
Concept Mouse Embryonic Stem Cells
Grant Discovering the epigenetics of RNA modifications
Grant RNA methylation and regulatory T cells
Grant Interrogation of dynamic RNA modifications in beta cells in type 1 diabetes
Grant Recognition and mechanism of N6-methyl adenosine modifications
Grant Global Cysteine Modifications in Human Pathogens
Grant Direct Oxidative Nucleic Acids Demethylation
Grant Base-resolution sequencing of m6A in RNA
Grant Direct Oxidative Nucleic Acids Demethylation
Academic Article Advances in targeting RNA modifications for anticancer therapy.
Academic Article Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.
Academic Article METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity.
Academic Article YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs.
Academic Article Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation.
Academic Article YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
Academic Article PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines.
Academic Article PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines.
Academic Article Ex vivo gliadin stimulation of intestinal cells.
Academic Article RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation.
Academic Article Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma.
Academic Article Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research.
Academic Article Base-resolution quantitative DAMM-seq for mapping RNA methylations in tRNA and mitochondrial polycistronic RNA.
Academic Article BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution.
Academic Article FMRP phosphorylation modulates neuronal translation through YTHDF1.
Academic Article RNA m6A methylation and MDSCs: Roles and therapeutic implications for radiotherapy.
Academic Article Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome.
Academic Article 5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer.
Academic Article Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.
Academic Article 5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma.
Academic Article Chemical manipulation of m1A mediates its detection in human tRNA.
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  • human
  • leukemias